Mechanistic insights into antibacterial and antioxidant bacterial cellulose films functionalized with Vitex negundo extract
DOI:
https://doi.org/10.15282/cst.v5i2.14921Keywords:
Wound healing patch, Biopackaging materials, Vitex negundo, Bacterial celluloseAbstract
As the life sciences embrace sustainability, biocompatible and biodegradable materials with minimal ecological footprints are emerging as key enablers in various applications. Addressing the growing demand for sustainable and functional biomaterials, this study investigated how the incorporation of Vitex negundo (VN) extract influences the structural, chemical, and functional characteristics of alginate–bacterial cellulose (AB) films especially its antibacterial and antioxidant potential. AB films were prepared with varying concentrations of VN extract (0.25% and 0.5%). Physical characterization was performed through thickness measurement and Fourier-transform infrared spectroscopy (FTIR). The antibacterial potential was evaluated through the inhibition zone method, while the antioxidant potential was assessed using the DPPH radical scavenging assay. The findings contribute to the design of plant-extract-functionalized biopolymer films, underscoring the importance of extract concentration optimization. The results support the potential of VN–BC films as bioactive materials for various applications, while highlighting directions for future studies on mechanical stability, release kinetics, and industrial scalability.
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